Typeface is a visual representation of how you what words to be perceived. It is essentially symbols arranged together to communicate a specific responsiveness. Different collections of typeface impose different undertones relative to purpose.
What typeface you choose will be down to the design brief and usage. If it is designed to be read on your mobile device, to a university text book or a comic book would drastically differ because of its intended audience. It is a guideline for both the end user and the designer to follow and comply with.
Depending on what media the typeface would used for, the structure could change on a geographical basis due to the nature of the characters are used and the language chosen. Intended delivery would take into account the personality of the style linked with the functionality and intended impact. Make sure you have a some ideas of typography and calligraphy styles in mind when designing your typeface.